Do you know that there are different variants of Hashimoto thyroiditis?

  For long Hashimoto’s thyroiditis has been characterized as a well-defined clinicopathologic entity. Though nowadays it is considered a heterogeneous disease (has several etiologies). There are different variants of Hashimoto thyroiditis: – fibrous, fibrous atrophic (Ord’s disease), or goitrous forms – IgG4 thyroiditis Thyroid autoantibody levels differ between goitrous and atrophic thyroiditis in that inhibitory TSH receptor antibodies are higher in Ord’s thyroiditis. These antibodies block cAMP (a messenger, used for intracellular signal transduction) production[…]

Depression associated with a significantly increased risk of autoimmune disease

The etiology of autoimmune disease is still a debate and unclear. A population-based study including approximately 1.1 million people was conducted using linked Danish registries to investigate the association between depression and the risk of autoimmune disease. The findings show that depression to be associated with a significantly increased risk of autoimmune disease, compared to those without a history of depression. Results suggest a general increased risk of autoimmune diseases following the onset of depression during[…]

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