Do you know that there are different variants of Hashimoto thyroiditis?
For long Hashimoto’s thyroiditis has been characterized as a well-defined clinicopathologic entity. Though nowadays it is considered a heterogeneous disease (has several etiologies). There are different variants of Hashimoto thyroiditis: – fibrous, fibrous atrophic (Ord’s disease), or goitrous forms – IgG4 thyroiditis Thyroid autoantibody levels differ between goitrous and atrophic thyroiditis in that inhibitory TSH receptor antibodies are higher in Ord’s thyroiditis. These antibodies block cAMP (a messenger, used for intracellular signal transduction) production[…]